Physiological stress levelAcute and chronic strain
7 / 9Favourable
159
chronic stressacute stressno stress
Your body is coping well with current stress.
Sample report · Example data
Stress Monitor
Your stress regulation
What is measured is not stress itself, but how well your body regulates it. Six microRNAs from a single drop of capillary blood give an insight into the cellular control of your stress response.
- Report for
- Muster, Erika
- Sample collection
- 15.06.2026
- Material
- Dried blood spot card
- Scope
- 6 microRNAs
OverviewOverview
Stress Monitor
The other sample reports
Metabolic HealthHealthy AgingBiological Age ClockTelomere AnalysisStress MonitorHealthy SportThe principle
Your stress regulation. Not your stress level.
Stress is not a single quantity but a network of neuroendocrine, immunological and metabolic processes — controlled, among other things, via the HPA axis, inflammatory signalling pathways and mitochondrial adaptations. Six microRNAs are analysed: small, non-coding RNA molecules that help determine which genes are actually read under stress conditions.
Acute & chronic
How your stress response is currently running and whether a lasting burden is emerging.
Regulation
How well your body balances stress signals at the cellular level.
Long-term effects
How high the risk is that sustained stress will make itself felt in the long term.
The process
- 01
Measure
Dried blood spot card, fingertip. Six microRNAs, normalised to the reference gene miR-24-3p. No fasting required.
- 02
Evaluate
Two evaluations on the 1–9 scale: physiological stress level and risk of long-term effects.
- 03
Regulate
Targeted recommendations on plant-derived bioactive compounds and follow-up monitoring over time.
How do I read the scale?
Both evaluations and all six individual markers run on the scale from 1 to 9. Higher is always better: 1–3 red, 4–6 amber, 7–9 green. Each of the two evaluations additionally carries its own zone labelling.
13579
- 1–3 · Red
- Highest priority.
- 4–6 · Amber
- Take targeted countermeasures.
- 7–9 · Green
- Maintain the result.
Important
This report is not a diagnosis and does not replace medical or psychotherapeutic advice. If strain, exhaustion or sleep problems persist, please seek medical advice.
- The six microRNA values describe a snapshot in time and can be influenced through lifestyle — which makes them suitable for monitoring over time.
Results at a glance
Your two evaluations.
Risk of long-term effectsLong-term regulation
4 / 9Elevated
159
high riskmoderate risklow risk
Elevated risk — preventive action recommended.
The six individual markers
All microRNAs at a glance.
| microRNA | Designation | Level of regulation | Value | Feeds into |
|---|---|---|---|---|
| miR-21-5p | Cell protection indicator | Cellular protective and adaptive mechanisms | 8 / 9 | Long-term effects |
| let-7a-5p | Acute stress indicator | Baseline inflammatory regulation | 7 / 9 | Stress level |
| miR-16-5p | Serotonin-regulating indicator | Serotonergic regulation | 6 / 9 | Long-term effects |
| miR-15a-5p | Neuronal indicator | Neuronal stability and adaptation | 5 / 9 | Long-term effects |
| let-7g-5p | Chronic stress indicator | Inflammatory and metabolic regulation | 4 / 9 | Stress level |
| miR-106b-5p | Immune signal activating indicator | Immunological activation | 3 / 9 | Long-term effects |
Table scrolls sideways
The two evaluations are calculated by the laboratory from the microRNAs assigned to them; they are not the average of these individual values.
Evaluation 01
Physiological stress level.
Composed of the acute and the chronic stress indicator (let-7a-5p, let-7g-5p).
7 / 9Favourable
159
chronic stressacute stressno stress
The evaluation shows where your current stress response lies between ‘no stress’ and ‘chronic stress’. Your value is in the favourable range — your body is coping well with current stress. The assessment is always made in the context of the other markers.
Evaluation 01
The two individual indicators.
let-7a-5pAcute stress indicator
7 / 9
159
Part of the let-7 family; regulates inflammatory signalling pathways and is involved in stress and immune processes. The more favourable of the two values.
let-7g-5pChronic stress indicator
4 / 9
159
Regulates inflammatory and metabolic processes that influence systemic homeostasis. Markedly weaker than the acute indicator.
What matters here
The two individual indicators diverge widely: acute 7/9, chronic 4/9. The acute stress response is working; the chronic level is the weaker of the two.
- Four of the eleven recommendations — quercetin, EGCG, oleuropein and resveratrol — target precisely the chronic indicator let-7g-5p.
Recommendations
Compounds for evaluation 01.
| Compound | From marker | Source | Amount | Note |
|---|---|---|---|---|
| Butyrate | let-7a-5p · 7 | Pectin (apple, rosehip), inulin (chicory, artichoke) | at least 30 g/day | Formed during the fermentation of prebiotic fibre in the gut |
| Quercetin | let-7g-5p · 4 | Onion, capers, lovage, chives | at least 200 mg/day | Heat-sensitive — eat raw or prepare gently |
| EGCG | let-7g-5p · 4 | White or green tea (unfermented) | max. 800 mg/day | Piperine, vitamin C and fish oil improve bioavailability |
| Oleuropein | let-7g-5p · 4 | Olives, olive leaf, argan oil | 100 mg/day | Leaves are 3,000 times more concentrated, but very bitter |
Table scrolls sideways
Evaluation 02
Risk of long-term effects.
Calculated from four microRNAs: miR-16-5p, miR-15a-5p, miR-106b-5p and miR-21-5p.
4 / 9Elevated
159
high riskmoderate risklow risk
The evaluation does not yet show any acute stress-related overload. The risk of secondary conditions is, however, already elevated — it is worth acting here before long-term effects become manifest. This is the focus of your report.
Evaluation 02
The four microRNAs.
miR-106b-5pImmune signal
3 / 9
159
Regulates immune responses and inflammatory signalling pathways. The only red individual value in this report; four of the eleven recommendations address it.
miR-15a-5pNeuronal
5 / 9
159
Regulates neuronal processes, apoptosis and the cell cycle; influences neuronal homeostasis.
miR-16-5pSerotonergic
6 / 9
159
Regulates serotonergic signalling pathways and the serotonin transporter; involved in neuronal plasticity.
miR-21-5pCell protection
8 / 9
159
Regulates cell survival and apoptosis; involved in stress and repair processes. The best individual value in the entire report.
Recommendations
Compounds for evaluation 02.
| Compound | From marker | Source | Amount | Note |
|---|---|---|---|---|
| Resveratrol | miR-106b-5p · 3 | Grape skins, raspberries, lingonberries, strawberries | 150 mg/day | Hard to achieve through diet alone |
| Omega-3 (PUFAs) | miR-106b-5p · 3 | Oily fish, walnuts, algae, rapeseed and linseed oil | 250–500 mg/day | Keep omega-3 and omega-6 in balance |
| Berberine | miR-106b-5p · 3 | Barberry root bark, orange root | max. 500 mg/day | Known as a tea from Ayurvedic medicine |
| Folate | miR-16-5p · 6 | Green leafy vegetables, spinach, kale, broccoli | 300 µg/day | Smoking reduces uptake |
Table scrolls sideways
All recommendations at a glance
Your interventions.
Eleven compounds, each assigned to the microRNA marker it acts on, together with that marker’s current value. Sorted by urgency — the weakest markers first.
| Compound | From marker | Source | Amount | Note |
|---|---|---|---|---|
| Resveratrol | miR-106b-5p · 3, let-7g-5p · 4, miR-15a-5p · 5 | Grape skins, raspberries, lingonberries, strawberries | 150 mg/day | Hard to achieve in this amount through diet alone |
| Berberine | miR-106b-5p · 3 | Barberry root bark, orange root | max. 500 mg/day | Known as a tea from Ayurvedic medicine |
| Butyrate | miR-106b-5p · 3, let-7a-5p · 7, miR-21-5p · 8 | Pectin (apple, rosehip), inulin (chicory, artichoke) | at least 30 g/day | Formed during the fermentation of prebiotic fibre in the gut |
| Omega-3 (PUFAs) | miR-106b-5p · 3, miR-21-5p · 8 | Oily fish, walnuts, algae, rapeseed and linseed oil | 250–500 mg/day | Keep omega-3 and omega-6 in balance |
| Quercetin | let-7g-5p · 4 | Onion, capers, lovage, chives | at least 200 mg/day | Heat-sensitive — eat raw or prepare gently |
| Oleuropein | let-7g-5p · 4 | Olives, olive leaf, argan oil | 100 mg/day | Leaves are 3,000 times more concentrated, but very bitter |
| EGCG (green tea) | let-7g-5p · 4, miR-15a-5p · 5 | White or green tea (unfermented) | max. 800 mg/day | Piperine, vitamin C and fish oil improve bioavailability |
| Folate | miR-16-5p · 6 | Green leafy vegetables, spinach, kale, broccoli | 300 µg/day | Smoking reduces uptake |
| Curcumin | miR-21-5p · 8 | Turmeric | max. 300 mg/day | Check with a doctor in case of pregnancy or gallstones |
| Gingerol | miR-21-5p · 8 | Ginger root | max. 5 g/day | During pregnancy only after consultation |
| Sulforaphane | miR-21-5p · 8 | Cruciferous vegetables, cabbage, broccoli (sprouts) | 25 mg/day | Best raw or briefly steamed |
Table scrolls sideways
Please review food supplements individually and in consultation with a qualified professional — particularly in the case of pregnancy, pre-existing conditions or concurrent medication. This overview does not replace medical advice.
Trend
Two measurements compared.
A comparison of your two measurements to date. Only measured values are shown — no prognosis.
15.03.202615.06.2026
Physiological stress level
6 / 9→7 / 9+1Favourable
Risk of long-term effects
5 / 9→4 / 9−1Elevated
What the trend shows
The two evaluations are moving in opposite directions: the current stress level has improved from 6 to 7 and is now in the green range. The value for long-term effects has fallen from 5 to 4 over the same period — and because a higher value here means a lower risk, this means the risk has increased.
- This is the real finding of this measurement: acute strain is being coped with better, while the long-term regulatory level has deteriorated. A good stress level alone says nothing about the long-term effects level.
- The two measurements were around three months apart. The interval until the next follow-up measurement is set by the supervising institution.
Summary
Your focus: the long view.
Your current stress level is good — and that is precisely the point at which this report pushes back: the level that has deteriorated is the one you cannot feel.
01
miR-106b-5p — the only red individual value
At 3/9, the immune signal activating indicator is the weakest value in the report and feeds into the risk of long-term effects. Four of the eleven recommendations target it: resveratrol, berberine, butyrate and omega-3. In concrete terms: at least 30 g of fibre daily for butyrate formation in the gut, 250–500 mg of omega-3 from oily fish, walnuts or algal oil, plus berries for resveratrol.
02
let-7g-5p — the chronic level
At 4/9, the chronic stress indicator lies well below the acute one (7/9) — even though the evaluation as a whole is in the green range. The report does not show which of the two indicators carried the improvement from 6 to 7. Quercetin, EGCG, oleuropein and resveratrol act on the chronic level. The preparation notes differ from compound to compound — details in the table on page 06.
Maintain
miR-21-5p (8/9) and let-7a-5p (7/9) are the two strongest values — cellular protective mechanisms and the acute stress response are working well. Curcumin, gingerol and sulforaphane serve to maintain here, not to correct.
Follow-up and next step
- Your two measurements to date were around three months apart. The interval until the next follow-up is set by the supervising institution.
- For comparability, sample collection and time of day should remain similar.
- In cases of persistent exhaustion, sleep problems or low mood, this report does not replace medical assessment.
Questions about your report?
Discuss the results with the institution that carried out the sample collection. That is where the context needed to interpret them is held.
Contact
- contact@polarisdx.net
- +49 152 2858 0999
- www.polarisdx.net
Distribution
- Polaris Diagnostics Europe GmbH
- Große Bleichen 1–3
- 20354 Hamburg
Sample report. All values and personal details in this document are fictitious and serve solely to illustrate the report format. This is not a real report.
Interpretation. This report is not a diagnosis and does not replace medical or psychotherapeutic advice. The microRNA values describe a snapshot of cellular regulation; they are not a measurement of perceived stress and make no statement about the presence or development of a disease. If strain, exhaustion, sleep problems or low mood persist, please seek medical advice.
Legal framework. The laboratory analysis is carried out by our cooperation partner. Polaris Diagnostics Europe GmbH is responsible for distribution and support. Please review food supplements individually and in consultation with a qualified professional.
© 2026 Polaris Diagnostics Europe GmbH · As at: August 2026
All six documents are sample reports: every value, genotype and personal detail is fictitious and serves solely to illustrate the report format. These are not real results.
The other sample reports