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Current event: MEDICA 2026

Infection & inflammation

Interpreting infection and inflammation markers in context

CRP, PCT, IL-6 and ferritin can provide different information about inflammatory processes. Their meaning depends on the question, timing and clinical context; no single value establishes a diagnosis or treatment decision.

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A marker is not a diagnosis

Signs of infection and inflammation can overlap and change over time. Measurements therefore need to be assessed alongside symptoms, history, timing and, where appropriate, further diagnostics rather than using one value to infer a cause.

Professional care contexts

  • Outpatient practices and medical facilities with defined infection or inflammation questions
  • Clinical teams that place measurements within established intake, follow-up or aftercare processes
  • Professional healthcare providers with clear responsibility for measurement, documentation and further assessment

Questions before selection and interpretation

  • Which specific infection or inflammation question should the measurement support?
  • Which available marker provides complementary information for that question and at what time?
  • Which findings require confirmation, follow-up measurement or further diagnostics within the applicable care pathway?

Markers named in the existing service context

  • CRP (C-reactive protein)
  • PCT (procalcitonin)
  • IL-6 (interleukin-6)
  • Ferritin

From the question to professional interpretation

  1. Clarify context and responsibility

    Define the reason, care setting and responsibility for interpretation and next steps before measurement.

  2. Perform and document the measurement

    Handle the sample and measurement according to the instructions for the specific test in use, documenting time and result.

  3. Assess the result as part of the whole picture

    Do not use the value in isolation; combine it with the clinical context and, where appropriate, confirmatory or further diagnostics.

Professional note

Infection and inflammation markers provide context-dependent diagnostic information. They do not replace individual medical assessment, diagnosis, urgency decisions or treatment and do not guarantee a particular cause or outcome.

Frequently asked questions

Questions about infection and inflammation markers